Saturday, August 31, 2019
Franklin Delano Roosevelt: The Labor Leader Essay
Political Background            Franklin D. Roosevelt was the longest running president of the United States. He was at the helm of the nation from the end of the Great Depression to the end of the Second World War. Spanning 12 years, his administration faced the toughest times in U.S. history. However, his policies and programs must have effectively addressed both foreign and domestic crises as evidenced by the popular will that kept him in the White House.            FDR entered politics as a democrat and won a seat in the New York Senate in 1910 as well governorship of New York in 1928. He was an advocate of the farmers in New York and an opponent of corruption in government which manifested in the activities of the Tweed Ring (Miller Center, 2008). His style of governance was both progressive and nationalist where he believed in equality among peoples and accountability of government.            He became assistant secretary to the navy then made his comeback as governor of New York in 1928 after years of battling with polio. His political career culminated in his election as United States president in 1932. He was re-elected thrice after but was unable to finish his last term because of his sudden death. Involvement in Labor Management Relations            Well before his inauguration and into the first years of his administration, he saw the crisis brought about by overproduction bring agriculture and manufacturing to a standstill into what is known as the Great Depression. Thousands of workers became unemployed and farmers were set to lose their farms and property to creditors. Poverty, hunger, joblessness and uncertainty lurked evidenced everywhere.            FDR believed that capitalism is the most advanced economy. However, it has its flaws if unregulated so that necessary reforms should be made to enable government to regulate the economy (Miller Center, 2008). At the height of the Great Depression, FDR’s early solution to U.S. industry was encapsulated in the National Industry Recovery Act.            The NIRA sought to stimulate production by creating demand for products through public works construction (Miller Center, 2008). This in turn generated employment for the multitudes of jobless Americans. The Act also gave incentives to industry and at the same time provided protection for workers in terms of wage regulation and the right to collectively bargain and organize (Dubofsky, 1994, p.111). However, the NIRA was largely unsuccessful because it failed to take into account the basic laws that governed capitalism.            FDR tried a new tack through the Workers Progress Administration, the Wagner-Connery National Labor Relations Act and the Social Security Act. The WPA sustained and expanded the earlier efforts of job creation (Miller Center, 2008). Millions of Americans were paid by government to construct schools buildings, hospital facilities and transport infrastructure. It also provided the necessary training in order to be eligible for employment.            The Wagner-Connery Act was the successful attempt at legislating the worker’s welfare stated in the earlier NIRA. This Act ensured worker’s rights to collective bargain and union organization (Dubofsky, 1994, p.131). It further established a government agency to oversee its implementation – the National Labor Relations Board which became the workers union’s grievance center for the unfair wage and labor practices committed by company management (Dubofsky, 1994, p.128).            In 1938, FDR enacted the Fair Labor Standards Act to complement the Wagner-Connery Act. The FLSA set up a legal minimum working man’s wage and pegged the legal maximum hours of work each day as additional measures against worker exploitation (Miller Center, 2008). As a result, union membership ballooned to more than 10 million by the 1940’s.            The Social Security Act instituted welfare benefits for the workers such as assistance and insurance during old age, insurance for the unemployed, assistance to dependent children and the blind (Miller Center, 2008). The funds for this program were subtracted regularly from the worker’s wages. FDR further initiated a socialized tax scheme which aimed to tax the wealthier more and the workers less, though this was largely shot down by Congress.            The major economic problems involving industry during the Great Depression forced FDR to be involved with labor management. Workers formed the bulk of the electorate, and as a liberal reformer, he saw it his responsibility as a public official to improve their conditions. His sensitivity and knowledge regarding the unequal relations between management and workers enabled him to effectively translate workers’ rights into legislation. Contribution to Labor Management Relations            FDR has greatly contributed to labor management relations by creating legal mechanisms by which worker’s can exercise their rights and demand fairer wages along with better working conditions and benefits from management. These mechanisms are in due recognition of the fact that workers and management have contradictory interests: the former aims to obtain higher wagers while the latter aims to decrease production costs through lowered wages.            The labor and welfare acts that saw implementation during FDR’s administration are also evidence of the worker being in a disadvantaged position. It recognized that the only manner in which workers can engage management with regards to their remuneration and work environment is through their collective bargaining. In order for workers to be forceful, they must consolidate themselves into a union as their venue for organized action.            The Wagner Act and the Fair Labor Standards Act also point to the need for government arbitration in labor disputes with the National Labor Relations Board as the mediating agency between unions and management. List of References Dubofsky, M. (1994). The State and Labor in Modern America. North Carolina: University      of North Carolina Press. Retrieved 25 March 2008 from       http://www.questia.com/read Miller Center Public Affairs University of Virginia (2008). American President: An Online      Reference Resource – Franklin Delano Roosevelt (1882-1945). Retrieved 25 March 2008 from http://millercenter.org/academic.
Friday, August 30, 2019
The Science Behind The Desalination Process Environmental Sciences Essay
Desalination is the procedure of taking salt from salty H2O to do it suited for imbibing or for usage by industries that require really pure H2O. ( Water Corporation Australia, 2011 ) Desalination workss are normally located near sea or ocean as most desalinization workss get the salty H2O from the sea and ocean. There are many ways of taking the salt from H2O but the chief 3 procedures are: Electrodialysis, Thermal distillment and Reverse osmosis. Electrodialysis Salts dissolved in H2O are ionic which mean they can be either be positively charged ions or negatively charged ions. When an electrical charged is passed through the H2O so â€Å" opposites attract †happens the salt ions will travel toward the antonym charged for illustration a positively charged salt ion will travel toward a negative charge, a negatively charged salt ion will travel toward the positively charge. Once the salt ions have move towards the antonym charged you will hold separated salt from H2O. A membrane is used to divide the purified H2O and salt ions. Thermal distillment The procedure in which salt H2O from the sea or ocean is heated to bring forth steam, so the steam will be condensed on a cold surface and H2O will be left behind. Rearward Osmosis Rearward Osmosis is uses a really high force per unit area and a really all right membrane to roll up the fresh H2O from the salty H2O. The membrane is like a strainer it has holes on the strainer which the holes are merely little plenty to let H2O eyeglasss pass through but non allow salt eyeglasss and other drosss to go through though the membrane Electrodialysis Rearward OsmosisBenefitsThe benefits of desalinization are that you can easy happen the resource, 97 % of the H2O is in ocean and sea and all of that is salt H2O which means that companies and authoritiess can construct desalinization workss and can be certain that the desalinization works will acquire a changeless supply of H2O. For illustration a Government decides to construct a desalinization works and they locate the works merely off shore from the major metropolis, they have a pipe connected to the major metropolis and they turn the desalinization works on H2O is now being filtered by the procedure contrary osmosis all of a sudden you have merely created another really sustainable H2O supply for you metropolis and you have reduced the sum of H2O that needs to be extracted from the chief river. Another benefit of constructing a desalinization works is that the H2O is besides really clean after the filtering and does non necessitate external 3rd party cleansing which river H2O do es. When the desalinization works finished the procedure of filtrating out the salt from the seawater the H2O is really pure so it does non necessitate to travel through extra cleansing, the filtered H2O from the desalinization works may merely necessitate Cl to be added to the H2O and it would be absolutely potable and clean and pure and it would be more cost effectual merely to make all the procedure, filtrating salt and so adding Cl to filtered H2O all in the one desalinization works. Another benefit is that desalinization is more â€Å" socially †accepted than effluent recycling ( Which is H2O from lavatories, cloacas etc ) authoritiess would be much more successful seeking to sell desalinization to the populace than seeking to sell recycled H2O from your lavatories.DisadvantagesDesalination workss are really inefficient and research suggest that if a desalinization works pumps in 500million litres of H2O and so filtrate that 500litres so 250million litres would be pure H2O and the other 250million litres would be salt and drosss which so is pumped back into sea or ocean merely job being that salt and drosss is twice the dressed ore of salt than seawater which means when the following burden of H2O comes in it will be more concentrated than the burden before which mean the desalinization it would be more salt than H2O so the efficiency of the desalinization workss goes down even more. Another downside of a desalinization works is that it uses a batch of energy to power the works which means that it is consuming our energy resources which is already on a strain so fundamentally they are seeking to repair the H2O crisis but making more quandary for the nursery effects and planetary heating issue. But being run on electricity is another issue what happens if they metropolis all of a sudden had a black out, even though the desalinization works may hold backup generators they wo n't be able to keep a power for a works every bit large as a desalinization works, so if we had a power blackout would that average half of the metropolis H2O supply is gone or if we rely entirely on the desalinization works it would intend that the whole metropolis H2O supply is gone which would be really troublesome for the metropolis. Another disadvantage is that â€Å" nil is perfect †no affair how perfect the engineering is it non hone and if something all of a sudden goes incorrect say in rearward osmosis the membrane is excessively big and salt and drosss manage to go through through it would non merely endanger the occupant of metropolis its supply H2O but cause a batch of people to be ill or even dices.Social effects of desalinizationPeoples can still be really disbelieving about imbibing H2O from the sea or ocean even though scientist and applied scientists of the desalinization works says the H2O is absolutely safe, there is ever on the dorsum of your head, what if some went incorrect and they H2O is non wholly pure? Would you desire to give that H2O to your kids, your babe, and your aged parents? With desalinization there is ever that thought that it is non wholly clean, it ‘s truly salt H2O filtered a twosome of clip to acquire pure H2O. Which is turn affects us socially because that it ever traveling to be a difficult sell for authoritiess to state to their occupants that this H2O is absolutely clean.Economic effects of desalinizationDesalination workss are really expensive and they money has to come from someplace so revenue enhancement remunerators end up paying for the desalinization works which obviously makes it even a harder sell for authoritiess, now non merely you have a H2O supply which is less dependable and possible less pure than fresh river H2O you have to pay for this less dependable and less pure beginning of H2O. They H2O measures will hold to travel up every bit good non merely will they charged a levy to pay for the desalinization works they will do you pay excess to subsidies the cost of running the works ( Electricity, paying staff etc )Environmental effects of desalinizationWhen you build a desalinization works merely of shore you besides could perchance interrupt the natural home ground of certain animate beings like fish or they would hold to clear land and which means they will pass over certain types of creates out of their natural home ground which is non ideal, you killing of species and damaging the land. As mentioned before desalinization workss use a batch of power so it will consume fossil fuels and add the turning job of nurseries gas and planetary heating and C emanations as good.DecisionDesalination is a really feasible and realistic solution for H2O direction, it can work out the H2O crisis presently is seem like desalinization is the best alternate solution for H2O in many major metropoliss around the word as it easier accessible engineering is instead mature downside being its really inefficient and cost a batch of money and uses a batch of power. But their possibly better or every bit good solution out at that place instead than desalinization like waste/storm H2O recycling which is a effectual manner of supplying a secondary H2O supply but with societal effects which people non wishing the fact they are re imbibing their lavatory H2O. A more feasible solution possibly is rainwater reaping in which persons can roll up rainwater and utilize it for their demand which major societal or economical affect merely job being that you can truly merely collect rainwater when it rains hence is atrocious inefficient and non dependable. So in stating all of that, Desalination is the best technique to work out our H2O crisis.
Thursday, August 29, 2019
Breast Cancer
Some methods used to diagnose breast carcinoma are mammograms, MRI’s, and biopsies (NCI, 2010). A staging system is standardized way for the cancer care team to summarize information about how far a cancer has spread (ACS, 2012). The most common system used to describe the stages of breast cancer is the American Joint Committee on Cancer (AJCC) TNM system (ACS, 2012). Each stage has different prognoses with varying survival rates as well (Marissa, 2011). There are also many ways to prevent breast cancer including maintain a healthy weight, avoiding the alcohol consumption, and by getting an annual mammogram (Reynolds, 2010). A genetic mutation that raises the risk of breast cancer is found in up to 60 percent of U. S. women, making it the first truly common breast cancer susceptibility gene (Metcalf Metcalf, 2008). Other breast diseases besides breast cancer are breast fat necrosis and fibrocystic breast disease (Sacks, 2011; Silverman, 1994). These diseases do not necessarily lead to breast cancer and can be treated (Sacks, 2011; Silverman, 1994). Keywords: – breast cancer, ducts, lobules, tumor, invasive (infiltrating carcinoma), noninvasive (noninfiltrating carcinoma), Ductal Carcinoma In Situ (DCIS), Invasive Lobular Carcinoma (ILC), intraductal carcinoma, nonfunctioning breast tissue, estrogen, lymph nodes, mammogram, MRI (magnetic resonance imaging), core biopsy, somatic mutations, fine needle aspiration biopsy, stereotactic biopsy, FGFR2, BRCA1, BRCA2, CDH1, PTEN, STK11, AR, ATM, BARD1, BRIP1, CHEK2, DIRAS3, ERBB2, NBN, PALB2, RAD50, metastasis, fat necrosis, fibrocystic breast disease Breast Cancer Cells are the building blocks of living things and cancer grows out of normal cells in the body (Dugdale, 2010). Cancer is the uncontrolled growth of abnormal cells in the body (Dugdale, 2010). Cancer harms the body when damaged cells divide uncontrollably to form lumps or masses of tissue called tumors (except in the case of leukemia where cancer doesn’t allow normal blood function by abnormal cell division in the blood stream (Peter, 2011). Normal cells in the body follow an orderly process of growth, division, and death, this is called apoptosis, and when this process breaks down, cancer begins to form (Peter, 2011). Cancer has been around since prehistoric times, and breast cancer is one of the earliest forms to have been mentioned (Eisenpreis, 1999). In the United States, breast cancer death rates are higher than those for any other cancer, besides lung cancer (breastcancer. org, 2012). Today, about 1 in 8 women (12%) will develop breast cancer in her lifetime (Martin, 2012). Breast cancer is a cancer that starts in the tissues of the breast (Yi-Bin David, 2011). In rare cases, breast cancer can start in other areas of the breast (Yi-Bin David, 2011). Breast cancer can be invasive or noninvasive (Yi-Bin David, 2011). Invasive meaning it has spread from the milk duct (lobule) to the other tissues in the breast (Eisenpreis, 1999). Noninvasive means that it has not yet invaded other breast tissue (Yi-Bin David, 2011). Types of Breast Cancer Breast cancer can begin in different areas of the breast – the ducts, the lobules, or sometimes, the tissue in between (breastcancer. org, 2012). There are several different types of breast cancer, including breast cancer in men (breastcancer. org, 2012). Some include Ductal Carcinoma In Situ, Invasive Lobular Carcinoma, and Male Breast Cancer (breastcancer. rg, 2012). Ductal carcinoma in situ (DCIS), or intraductal carcinoma, is a noninvasive breast cancer in the lining of the milk ducts that has not yet invaded nearby tissues of the breast (Yi-Bin David, 2011). It may progress to invasive cancer if it is left untreated (Yi-Bin David, 2011). DCIS is the earliest form of breast cancer and is usually found during a mammogram done as part of breast cancer screening (Mayo Clinic Staff, 2011). Because of the increased use of mammograms, the rate at which DCIS is diagnosed has increased dramatically in recent years (Mayo Clinic Staff, 011). When a woman has DCIS, she is at higher risk for the cancer coming back or also at higher risk for developing a new breast cancer than a person who has never had breast cancer before (breastcancer. org, 2012). Experts believe that 20 to 50% of women with DCIS will later develop an invasive breast cancer within 10 years of the DCIS diagnosis (Hoffman, 2010). The risk of lymph node involvement with ductal carcinoma in situ is only 1% to 2% so the lymph nodes under the arm do not need to be removed, as may be the case with other types of breast cancer (Hoffman, 2010). In seven out of 10 cases, breast-conserving lumpectomies – instead of mastectomies – were an effective treatment option (Hoffman, 2010). This will depend upon the size of your tumor and the extent of its spread throughout your breast and the surrounding lymph nodes (Hoffman, 2010). While DCIS isn’t life-threatening, it does require treatment to prevent the condition from becoming invasive (Mayo Clinic Staff 2011). Most recurrences happen within 5 to 10 years after the first diagnosis and the chances of that happening are under 30 percent (breastcancer. rg, 2012). Invasive Lobular Carcinoma is an invasive type of breast cancer that begins in the milk-producing glands (lobules) of the breast (Mayo Clinic Staff, 2011). When a person has ILC, this means that the cancer cells have broken out of lobule where they started and they now have the potential to spread to other areas or tissues of the body (Mayo Clinic Staff, 2011). This type of cancer is more difficult to se e on imaging because of the way it grows with spreading branches (Hopkins, 2012). The treatments for invasive lobular carcinoma fall into two broad categories: Local and Systemic Treatment. Local treatments treat the tumor and the areas surrounding it, such as the chest and lymph nodes (breastcancer. org, 2012). Systemic treatments travel throughout the body to destroy any type of cancer cells that may have left the original tumor and traveled to other tissues to reduce the risk of the cancer coming back (breastcancer. org, 2012). ILC cells can proceed to infiltrate fatty tissue and create a web-like mass (Stephan, 2008). This web of cancer cells may feel like a thickened area of breast tissue, and may not cause concern or pain at first (Stephan, 2008). Unfortunately, if it is left undetected, ILC can develop into a mass that is about ? inch ( 2 centimeters) to about 2 inches (5 centimeters) or bigger in size, before causing more noticeable symptoms (Stephan, 2008). Breast cancer in men is a very rare disease (Attebery, Adams ; Weiss, 2011). But the truth is that boys and girls, men and women all have breast tissue (Attebery, Adams ; Weiss, 2011). Men have a small amount of nonfunctioning breasts tissue (breast tissue that cannot produce milk) that is concentrated in the area directly behind the nipple on the wall of the chest (Attebery, Adams ; Weiss, 2011). A type of breast cancer that has spread outside of the duct and into the surrounding tissue is called invasive or infiltrating carcinoma (ASC, 2012). Some symptoms that may occur in males developing breast cancer include lumps, changes to the nipple or breast skin, or discharge of fluid from the nipple (National Cancer Institute, 2011). Men who have an altered gene related to breast cancer have an increased risk of developing breast cancer (National Cancer Institute, 2012). The major problem is that breast cancer in men is more often than not diagnosed later than breast cancer in women because men are less likely to be suspicious of an abnormality in that area (Wax, 2012). Also, their small amount of breast tissue is harder to feel, making it more difficult to catch these cancers early, and allowing tumors to spread more quickly to the surrounding tissues (Wax, 2012). Breast cancer in men is detected the same way as breast cancer is detected in women – through self-examination, clinical examination, or mammography (x-ray of the breast) (ASC, 2012). Methods for Diagnosis Breast cancer is sometimes found after symptoms appear, but many women with early breast cancer have no symptoms (American Cancer Society, 2011). This is why getting the recommended screening tests before any symptoms develop is so important (American Cancer Society, 2011). Three types of methods used for diagnosis are mammograms, MRI’s, and biopsies (NCI, 2010). A mammogram is a low-dose x-ray picture of the breast and can be used to check for breast cancer in women who don’t have any signs or symptoms of the disease. (NCI, 2010) The results are recorded on x-ray film or directly into a computer for a doctor called a radiologist to examine (Webmd, 2010). There are different types of mammograms including Screening mammograms and Diagnositc mammograms (Webmd, 2010). Mammograms detect tiny bits of calcium that develop in dead cancer cells (Hoffman, 2010). As more and more cancer cells age and die, theses calcifications grow nd on the mammogram, they appear as a shadowy area (Hoffman, 2010). Current guidelines from the American College Radiology, the American Cancer Society, and the Society for Breast Imaging recommend that women receive annual mammograms starting at age 40, even if they have no symptoms or family history of breast cancer (ACR, 2010). For every 1,000 women who have screening mammogram: 100 are recalled to get more mammogr aphy or ultrasound images, 20 are recommended for needle biopsy and 5 are diagnosed with breast cancer (ACR, 2010). A mammography unit is a rectangular box that houses the tube in which x-rays are produced (Radiological Society of North America, 2011). Once it is carefully aimed at the part of the body being examined, an x-ray machine produces a small burst of radiation that passes through the body, recording an image on photographic film or a special digital image recording plate (Radiological Society of North America, 2011). A brief medical history and a history of specific problems related to the breast, such as pain or a palpable lump (one that is felt), is obtained prior to the mammogram (Stoppler, 2011). All jewelry and clothing in the chest and breast area are removed prior to the mammogram (Stoppler, 2011). The patient’s breasts are then placed on a firm flat panel and a gentle, but firm pressure is applied to the breast with another panel, resulting in compression of the breast between the two panels (Stoppler, 2011). The compression of the breast is necessary to obtain quality mammograms and spreads the breast tissue out so that the x-ray image displays the inner breast tissue with good resolution (Stoppler, 2011). Dense bone absorbs much of the radiation while soft tissue, such as muscle, fat and organs, allow more of the x-rays to pass through them (Radiological Society of North America, 2011). As a result, bones appear white on the x-ray, soft tissue shows up in shades of gray and air appears black (Radiological Society of North America, 2011). The results of the mammogram can be given to the patient either by the radiologist at the completion of the mammogram or by the patient’s doctor who ordered the mammogram (Stoppler, 2011). An abnormal mammogram does not mean you have cancer (Stoppler, 2011). In some cases, it may just be an area of thicker or denser breast tissue, a cyst, or a benign lump such as a fibro adenoma (Stoppler, 2011). Unlike mammography which uses low dose x-rays to produce an image of the breast, MRI (Magnetic Resonance Imaging) uses powerful magnetic fields and radio waves to create images of the breast (Imaginis, 2012). The MRI system has the ability to switch magnetic fields and radio waves to achieve views in any plane and from any orientation while x-ray mammography requires re-orientation of the breast and mammography system for each view desired (Imaginis, 2012). MRI is a huge magnet and the woman gets put in the middle of the magnet; the magnetic field is turned on and then turned off again (Eisenpreis, 1999). The way the magnetized cells return to normal gives an image (Eisenpreis, 1999). The MRI finds lumps better than it tells whether or not they are cancerous (Eisenpreis, 1999). However, MRI can be good at showing how big a cancer is, once it has been found on the mammogram (Eisenpreis, 1999). A breast biopsy removes a sample of breast tissue that is looked at under a microscope to check for breast cancer and is usually done to check a lump found during a breast examination or a suspicious area found on a mammogram, ultrasound, or magnetic resonance imaging (MRI) (Marshall, 2009). During a fine-needle aspiration biopsy, the doctor inserts a thin needle into a lump and removes a sample of cells or fluid (Marshall, 2009). Nowadays, doctors might have decided to do something called stereotactic biopsy, where a patient lies on a table, with her breasts hanging down (Eisenpreis, 1999). A mammogram is taken to show where the lump is and a device holding a needle quickly shoots in and removes a few cells from the lesion (Eisenpreis, 1999). There is also something called a core biopsy that uses a larger needle to take out a piece of tissue, instead of just cells (Eisenpreis, 1999). A doctor numbs your skin with a shot of numbing medicine where the biopsy needle will be inserted and once the area is numb, a small cut is made in the skin from where the needle with a special tip is inserted into breast tissue (Marshall, 2009). Three to twelve samples will be taken to acquire the most accurate results (Marshall, 2009). Classifications and Associated Prognoses The stages of breast cancer are usually expressed as a number on a scale of 0 through IV – with stage 0 describing non-invasive cancers that remain within their original location and stage IV describing invasive cancers that have spread outside the breast to other parts of the body (Marisa, 2011). Cancer stage is based on four characteristics; the size of the cancer, hether the cancer is invasive or non-invasive, whether the cancer is in the lymph nodes, whether the cancer has spread to other parts of the body beyond the breast (Marisa, 2011). Sometimes doctors use the term â€Å"locally advanced†or regionally advanced†to refer to large tumors that involve the breast skin, underlying chest structures, changes to the breast’s shape, and lymph node enlargement that is visible or that the doctor can feel during an exam (Marisa , 2011). The three ways that cancer spreads in the body are: Through tissue where cancer invades surrounding normal tissue, through the lymph system where the cancer invades the lymph system and travels through the lymph vessels to other places in the body, and through the blood, where cancer invades the veins and capillaries and travels through the blood to other places in the body (NCI, 2009). When cancer cells break away from the primary (original) tumor and travel through the lymph nodes or blood to other places in the body, another (secondary) tumor may form (NCI, 2009). This process is called metastasis (NCI, 2009). The stage of the breast cancer can help the patient and the doctor understand the prognosis (the most likely outcome of the disease) and make decisions about treatment, along with all the other results in the pathology report (Marisa, 2011). A staging system is standardized way for the cancer care team to summarize information about how far a cancer has spread (ACS, 2012). The most common system used to describe the stages of breast cancer is the American Joint Committee on Cancer (AJCC) TNM system (ACS, 2012). The TNM staging system classifies cancers based on their T, N, and M stages (ACS, 2012). The letter â€Å"T†followed by a number 0 to 4 describes the tumor’s size and spread to the skin or to the chest wall under the breast (ACS, 2012). The letter â€Å"N†followed by a number from 0 to 3 indicates whether the cancer has spread to lymph nodes near the breast and, if so, how many lymph nodes are affected. The letter â€Å"M†followed by a 0 or 1 indicates whether the cancer has spread to distant organ (ACS, 2012). There are typically five stages (0 to 4) with sub-stages that indicate the prognosis for breast cancer (Lippman, 2005). Stage 0 where the carcinoma is insitu and no lymph nodes are affected had 99 percent 5 year survival rate (ACS, 2012). Stage IA also has a high rate, 92 percent, in which the tumor is equal to 2 centimeters (ACS, 2012). In stage IB, the tumor is 2 centimeters with micro metastases in 1 to 3 axillary lymph nodes but the cancer has not spread to distant sites (ACR, 2012). In stage IIA, the cancer cells have moved to the ipsilateral nodes and the 5 year survival rate lowers to 82 percent (Lippman, 2012). In stage IIB, the cancer cells have spread to movable ipsilateral nodes and the tumor is over 5 centimeters (Lippman, 2012). The 5 year survival rate lowers to 65 percent (ACS, 2012). In stage IIIA, there is no evidence of a primary tumor and no distant spreading (ACS, 2012). The 5 year survival rate lowers to 47 percent (Lippman, 2005). The tumor could be between 2 and 5 centimeters but there is still no distant spreading at this point (ACS, 2012). In stage IIIB the tumor has extended to the chest wall but there is still no distant metastases (Lippman, 2005). The 5 year survival rate lowers again to a 44 percent (Lippman, 2005). In stage IV the cancer can be any size (any T) and may or may not have spread to nearby lymph nodes (any N) (ACS, 2012). It has spread to distant organs or to lymph nodes far from the breast (M1) (ACS, 2012). The most common sites of spread are the bone, liver, brain, or lung (ACS, 2012). The survival rate lowers to 14 percent (Lippman, 2005). Prevention Methods Three ways to prevent breast cancer are by maintaining a healthy weight, avoiding alcohol consumption, and getting an annual mammogram (Reynolds, 2010). Mammogram screening, early diagnosis and better treatments have all contributed to the reduction in breast cancer cases by around 2 percent a year and the improved survival rate in the U. S. (Reynolds, 2010). Experts say now the focus needs to shift on improving personal lifestyle habits to prevent the disease even more (Reynolds, 2010). Early detection of breast cancer with screening mammography means that treatment can be started earlier in the course of the disease, possibly before it has spread (NCI, 2010). A medical team found an 11 percent lower risk of breast cancer in those women consuming the more healthful diet, including more whole grains, fruits and vegetables and less fatty, processed foods (Reynolds, 2010). They also found that those consuming large amounts of alcohol had a 21 percent increased risk (Reynolds, 2010). Drinking alcohol during adolescence has been linked to an increased risk of breast cancer, especially for girls with a family history of the disease (Reynolds, 2010). Exercise also plays a role in the reduction of breast cancer risk (Reynolds, 2010). In one study from the Women’s Health Initiative, as little as 1. 25 to 2. 5 hours per week of brisk walking reduced a woman’s risk by 18 percent (Reynolds, 2010). Walking 10 hours a week reduce the risk more (Reynolds, 2010). Diet and exercise can lead to weight reduction, another positive lifestyle change that can influence breast cancer disease risk (Reynolds, 2010). Many breast cancers are fueled by estrogen, a hormone produced in fat tissue (Reynolds, 2010). Experts suspect that more fat tissue equals more estrogen resulting in more cases of breast cancer that could possibly be avoided (Reynolds, 2010). Genetic ; Hereditary Influence According to researchers, the mutations in the gene, which is called FGFR2, raise the risk of breast cancer by 20 to 60 percent. (Metcalf ; Metcalf, 2008). A genetic mutation that raises the risk of breast cancer is found in up to 60 percent of U. S. omen, making it the first truly common breast cancer susceptibility gene (Metcalf ; Metcalf, 2008). Women with faulty copies of the genes BRCA1 or BRCA2 have 50 percent to 85 percent chance of getting breast cancer in their lifetimes, but they are rare genes and only account for 5 percent to possibly 10 percent of breast cancer cases (Metcalf ; Metcalf, 2008). Only 7% of all breast cancers are hereditary (Hirshaut ; Pressman, 2008). Of these hereditary cancers, 45% is caused by BRCA1 while 35% is caused by BRCA2 (Hirshaut ; Pressman, 2008). (Hirshaut ; Pressman, 2008). Variations of the BRCA1, BRCA2, CDH1, PTEN, STK11, and TP53 genes increase the risk of developing breast cancer (Chen, 2007). The AR, ATM, BARD1, BRIP1, CHEK2, DIRAS3, ERBB2, NBN, PALB2, RAD50, and RAD51 genes are associated with breast cancer (Chen, 2007). Cancers occur when a buildup of genetic mutations in critical genes – those that control cell growth and division or the repair of damaged DNA – allow cells to grow and divide uncontrollably to form a tumor (Honrado, Osorio, Palacios ; Benitez, 2006). These changes, which are called somatic mutations, are not inherited (Honrado, Osorio, Palacios ; Benitez, 2006). Less commonly, gene mutations inherited from a parent increase the risk of developing cancer (Honrado, Osorio, Palacios ; Benitez, 2006). In people with these inherited genetic changes, additional somatic mutations in other genes must occur for cancer to develop (Honrado, Osorio, Palacios ; Benitez, 2006). Additional factors that may influence a person’s risk of developing breast cancer include gender, age, ethnic background, a history of previous breast cancer, certain changes in breast tissue, and hormonal factors (Thompson ; Easton, 2004). A history of breast cancer in closely related family members is also an important risk factor, particularly if the cancer occurred at an early age (Thompson ; Easton, 2004). Women who have inherited certain mutations in these genes have a high risk of developing breast cancer, ovarian cancer, and several other types of cancer during their lifetimes (Thompson ; Easton, 2004). Inherited changes in several other genes, including CDH1, PTEN, STK11, and TP53, have been found to increase the risk of developing breast cancer (Thompson ; Easton, 2004). In hereditary breast cancer, the way that cancer risk is inherited depends on the gene involved (Walsh ; King, 2007). For example, mutations in the BRCA1 and BRCA2 genes are inherited in an autosomal dominant patter, which means one copy of the altered gene in each cell is sufficient to increase a person’s chance of developing cancer (Walsh ; King, 2007). In other cases, the inheritance of breast cancer risk is unclear (Walsh ; King, 2007). It is important to emphasize that people inherit an increased risk of cancer, not the disease itself (Walsh ; King, 2007). Not all people who inherit mutations in these genes will develop cancer (Walsh ; King, 2007). Other Breast Diseases Two other diseases found in the breast other than breast carcinoma are breast fat necrosis and fibrocystic breast disease (Sacks, 2011; Silverman, 1994). Fybrocystic breast disease is a commonly used phrase to describe painful, lumpy breasts (Sacks 2011). Hormones made in the ovaries can make a woman’s breasts feel swollen, lumpy, or painful before during menstruation each month (Sacks 2011). Fibrocysitc changes in the breast with the menstrual cycle affect over half of women (Sacks, 2011). Symptoms are usually worse right before the menstrual period, and then improve after the period starts (Sacks, 2011). Symptoms can include pain in both breasts, breasts that feel swollen and heavy, pain or discomfort under the arms, and thick or lumpy breasts (Sacks, 2011). This disease can be treated with medication like acetaminophen or ibuprofen (Sacks, 2011). Breast Fat necrosis is a benign condition that can occur in your breast (Silverman. 1994). It consists of fatty tissue that has been bruised, injured, or has died (Silverman, 1994). Once fatty tissue has been injured or has died, it can gradually change into scar tissue or may collect as liquid within an oil cyst (Silverman, 1994). Fat necrosis does not lead to the development of breast cancer, but it may sometimes cause breast pain (Silverman, 1994). An area of fat necrosis in your breast may feel like a fairly hard lump, or like a section of thick skin (Silverman, 1994). The person may see some drainage from the nipple that is nearest to the bruised region (Silverman, 1994). The nipple may sometimes even pull inward a little bit or the breast skin may dimple above the lump of fat necrosis (Silverman, 1994). Each case of fat necrosis is unique, so treatments will vary but if the fat necrosis has occurred recently, using warm compresses may help it subside (Silverman, 1994). When fat necrosis causes pain, the person can use ibuprofen and aspirin, but if that doesn’t help, ask your doctor if a prescription medication may be used (Silverman, 1994). About 39,520 women in the U. S. were expected to die in 2011 from breast cancer, though death rates have been decreasing since 1990  especially in women under 50 (â€Å"Learn about cancer,†2011). These decreases are thought to be the result of treatment advances, earlier detection through screening, and increased awareness (â€Å"breastcancer. org,†2012). References Peter, C. (2011, October 20). Medical news today. Retrieved from http://www. medicalnewstoday. com/info/cancer-oncology/ breastcancer. org. (n. d. ). (2012, March 14). Retrieved from http://www. breastcancer. org/symptoms/understand_bc/statistics. jsp Yi-Bin , C. , ; David , Z. (2011, 15 12). A. d. a. m. medical encyclopedia. Retrieved from http://www. ncbi. nlm. nih. gov/pubmedhealth/PMH0001911/ Mayo Clinic Staff. (2011, June 23). Ductal carcinoma in situ (dcis). Retrieved from http://www. mayoclinic. com/health/dcis/DS00983 Avon Foundation Breast Cancer (n. d. ). In http://www. hopkinsmedicine. org/avon_foundation_breast_center/breast_cancers_other_conditions/invasive_lobular_carcinoma. html. Stephan, P. (2008, July 24). Invasive Lobular Carcinoma. Retrieved from about. com website: http://breastcancer. about. com/od/types/p/ilc. html Dugdale, D. (2010, August 14). Pubmed. Retrieved from http://www. ncbi. nlm. nih. gov/pubmedhealth/PMH0002267/ Martin, L. (2012, January 18). Breast cancer facts. WebMD. Retrieved from http://women. webmd. om/guide/breast-cancer-arm-yourself-with-facts National Cancer Insitute. (2012). National cancer institute. Retrieved from http://www. cancer. gov/cancertopics/pdq/treatment/malebreast/Patient/page1 Attebery, L. , Adams, J. H. , ; Weiss, M. (2011, november 22). Male breast cancer. Retrieved from http://www. breastcancer. org/symptoms/types/male_bc/ National Cancer Institute. ( 2011). Male breast cancer. Retrieved from http://www. nlm. nih. gov/medlineplus/malebreastcancer. html Wax, A. (2011). Breast cancer in men: Symptoms, causes, treatments. Retrieved from http://www. webmd. com/breast-cancer/guide/breast-cancer-men American Cancer Society. (2011, September 29). American cancer society. Retrieved from http://www. cancer. org/Cancer/BreastCancer/DetailedGuide/breast-cancer-diagnosis NCI. (2010, September 22). National cancer institute. Retrieved from http://www. cancer. gov/cancertopics/factsheet/detection/mammograms Marshall, S. (2010, November 12). Webmd. Retrieved from http://women. webmd. com/mammogram-16573 Hoffman, M. (2010 February 18). Ductal carcinoma (invasive and in situ. Retrieved from http://www. webmd. com/breast-cancer/ductal-carcinoma-invasive-in-situ ACR. (2012). Mammography facts. Retrieved from http://www. ammographysaveslives. org/facts. aspx Hirshaut, Y. , ; Pressman, P. I. (2008). Breast cancer: The complete guide. (5th ed. ). New York, NY: Bantam Dell. Radiological Society of North America. (2011, June 24). Radiologyinfo. org. Retrieved from http://www. radiologyinfo. org/en/info. cfm? pg=mammo ASCO. (2011, January 26). Breast Cancer- Male Retrieved from http://www. cancer. net/patient/Cancer Types/Breast Cancer – Male/? skid= Stoppler, M. C. (2011). Medicinenet. Retrieved from http://www. medicinenet. com/mammogram/article. html Imaginis. (2012). Breast cancer mri – magnetic resonance imaging. Retrieved from http://www. maginis. com/mri-scan/magnetic-resonance-breast-imaging-mri-mr-3 Eisenpreis, B. (1999). A young woman’s guide to breast cancer prevention. New York: The Rosen Publishing Group. Marshall, S. (2009, April 29). Breast biopsy. Retrieved from http://women. webmd. com/breast-biopsy Metcalf, T. , Metcalf, G. (2008). Perspective on diseases and disorders. (1 ed. ). Michigan: Thomson Gale. Chen, S. ( 2007, April 10). Meta-analysis of BRCA1 and BRCA2 penetrance. Retrieved from http://ghr. nlm. nih. gov/condition/breast-cancer Honrado, E. , Osorio, A. , Palacios, J. , Benitez, J. (2006, September 25). Pathology and gene expression of hereditary breast tumors associated with brca1, brca2 and chek2 gene mutations. Retrieved from http://ghr. nlm. nih. gov/condition/breast-cancer/show/References Thompson, D. , Easton, D. (2004, July 9). The genetic epidemiology of breast cancer genes. Retrieved from http://ghr. nlm. nih. gov/condition/breast-cancer Walsh, T. , King, M. (2007, February 11). Ten genes for inherited breast cancer. Retrieved from http://ghr. nlm. nih. gov/condition/breast-cancer Marisa , W. (2011, August 03). Stages of breast cancer. Retrieved from http://www. breastcancer. org/symptoms/diagnosis/staging. jsp NCI. 2009). Breast cancer treatment (pdq). Retrieved from http://www. cancer. gov/cancertopics/pdq/treatment/breast/Patient/page2 Lippman, M. E. (2005). Cancer monthly. Retrieved from http://www. cancermonthly. com/cancer_basics/breast. asp American Cancer Society. (2012, March 06). Breast cancer. Retrieved from http://www. cancer. org/Cancer/BreastCancer/DetailedG uide/breast-cancer-staging Reynolds, D. (2010, March 26). Emaxhealth. Retrieved from http://www. emaxhealth. com/1506/98/36185/one-third-breast-cancer-cases-avoided-diet-and-exercise. html NCI. (2010, September 22). National cancer institute. Retrieved from http://www. cancer. ov/cancertopics/factsheet/detection/mammograms Sacks, D. N. (2011, November 16). Fibrocystic breast disease. Retrieved from http://www. nlm. nih. gov/medlineplus/ency/article/000912. htm Silverman, P. (1994, July). Breast fat necrosis – symptoms, causes and treatments. Retrieved from http://breastcancer. about. com/od/whenitsnotcancer/tp/Breast-Fat-Necrosis. htm American Cancer Society. U. S. Breast cancer statistics. (2011, September 29). Retrieved from http://www. cancer. org/Cancer/BreastCancer/index Hail, J. (2011, 09). National breast cancer foundation, inc.. Retrieved from http://www. nationalbreastcancer. org/About-Breast-Cancer/ Breast Cancer Breast Cancer Breast Cancer Some methods used to diagnose breast carcinoma are mammograms, MRI’s, and biopsies (NCI, 2010). A staging system is standardized way for the cancer care team to summarize information about how far a cancer has spread (ACS, 2012). The most common system used to describe the stages of breast cancer is the American Joint Committee on Cancer (AJCC) TNM system (ACS, 2012). Each stage has different prognoses with varying survival rates as well (Marissa, 2011). There are also many ways to prevent breast cancer including maintain a healthy weight, avoiding the alcohol consumption, and by getting an annual mammogram (Reynolds, 2010). A genetic mutation that raises the risk of breast cancer is found in up to 60 percent of U. S. women, making it the first truly common breast cancer susceptibility gene (Metcalf Metcalf, 2008). Other breast diseases besides breast cancer are breast fat necrosis and fibrocystic breast disease (Sacks, 2011; Silverman, 1994). These diseases do not necessarily lead to breast cancer and can be treated (Sacks, 2011; Silverman, 1994). Keywords: – breast cancer, ducts, lobules, tumor, invasive (infiltrating carcinoma), noninvasive (noninfiltrating carcinoma), Ductal Carcinoma In Situ (DCIS), Invasive Lobular Carcinoma (ILC), intraductal carcinoma, nonfunctioning breast tissue, estrogen, lymph nodes, mammogram, MRI (magnetic resonance imaging), core biopsy, somatic mutations, fine needle aspiration biopsy, stereotactic biopsy, FGFR2, BRCA1, BRCA2, CDH1, PTEN, STK11, AR, ATM, BARD1, BRIP1, CHEK2, DIRAS3, ERBB2, NBN, PALB2, RAD50, metastasis, fat necrosis, fibrocystic breast disease Breast Cancer Cells are the building blocks of living things and cancer grows out of normal cells in the body (Dugdale, 2010). Cancer is the uncontrolled growth of abnormal cells in the body (Dugdale, 2010). Cancer harms the body when damaged cells divide uncontrollably to form lumps or masses of tissue called tumors (except in the case of leukemia where cancer doesn’t allow normal blood function by abnormal cell division in the blood stream (Peter, 2011). Normal cells in the body follow an orderly process of growth, division, and death, this is called apoptosis, and when this process breaks down, cancer begins to form (Peter, 2011). Cancer has been around since prehistoric times, and breast cancer is one of the earliest forms to have been mentioned (Eisenpreis, 1999). In the United States, breast cancer death rates are higher than those for any other cancer, besides lung cancer (breastcancer. org, 2012). Today, about 1 in 8 women (12%) will develop breast cancer in her lifetime (Martin, 2012). Breast cancer is a cancer that starts in the tissues of the breast (Yi-Bin David, 2011). In rare cases, breast cancer can start in other areas of the breast (Yi-Bin David, 2011). Breast cancer can be invasive or noninvasive (Yi-Bin David, 2011). Invasive meaning it has spread from the milk duct (lobule) to the other tissues in the breast (Eisenpreis, 1999). Noninvasive means that it has not yet invaded other breast tissue (Yi-Bin David, 2011). Types of Breast Cancer Breast cancer can begin in different areas of the breast – the ducts, the lobules, or sometimes, the tissue in between (breastcancer. org, 2012). There are several different types of breast cancer, including breast cancer in men (breastcancer. org, 2012). Some include Ductal Carcinoma In Situ, Invasive Lobular Carcinoma, and Male Breast Cancer (breastcancer. rg, 2012). Ductal carcinoma in situ (DCIS), or intraductal carcinoma, is a noninvasive breast cancer in the lining of the milk ducts that has not yet invaded nearby tissues of the breast (Yi-Bin David, 2011). It may progress to invasive cancer if it is left untreated (Yi-Bin David, 2011). DCIS is the earliest form of breast cancer and is usually found during a mammogram done as part of breast cancer screening (Mayo Clinic Staff, 2011). Because of the increased use of mammograms, the rate at which DCIS is diagnosed has increased dramatically in recent years (Mayo Clinic Staff, 011). When a woman has DCIS, she is at higher risk for the cancer coming back or also at higher risk for developing a new breast cancer than a person who has never had breast cancer before (breastcancer. org, 2012). Experts believe that 20 to 50% of women with DCIS will later develop an invasive breast cancer within 10 years of the DCIS diagnosis (Hoffman, 2010). The risk of lymph node involvement with ductal carcinoma in situ is only 1% to 2% so the lymph nodes under the arm do not need to be removed, as may be the case with other types of breast cancer (Hoffman, 2010). In seven out of 10 cases, breast-conserving lumpectomies – instead of mastectomies – were an effective treatment option (Hoffman, 2010). This will depend upon the size of your tumor and the extent of its spread throughout your breast and the surrounding lymph nodes (Hoffman, 2010). While DCIS isn’t life-threatening, it does require treatment to prevent the condition from becoming invasive (Mayo Clinic Staff 2011). Most recurrences happen within 5 to 10 years after the first diagnosis and the chances of that happening are under 30 percent (breastcancer. rg, 2012). Invasive Lobular Carcinoma is an invasive type of breast cancer that begins in the milk-producing glands (lobules) of the breast (Mayo Clinic Staff, 2011). When a person has ILC, this means that the cancer cells have broken out of lobule where they started and they now have the potential to spread to other areas or tissues of the body (Mayo Clinic Staff, 2011). This type of cancer is more difficult to se e on imaging because of the way it grows with spreading branches (Hopkins, 2012). The treatments for invasive lobular carcinoma fall into two broad categories: Local and Systemic Treatment. Local treatments treat the tumor and the areas surrounding it, such as the chest and lymph nodes (breastcancer. org, 2012). Systemic treatments travel throughout the body to destroy any type of cancer cells that may have left the original tumor and traveled to other tissues to reduce the risk of the cancer coming back (breastcancer. org, 2012). ILC cells can proceed to infiltrate fatty tissue and create a web-like mass (Stephan, 2008). This web of cancer cells may feel like a thickened area of breast tissue, and may not cause concern or pain at first (Stephan, 2008). Unfortunately, if it is left undetected, ILC can develop into a mass that is about ? inch ( 2 centimeters) to about 2 inches (5 centimeters) or bigger in size, before causing more noticeable symptoms (Stephan, 2008). Breast cancer in men is a very rare disease (Attebery, Adams ; Weiss, 2011). But the truth is that boys and girls, men and women all have breast tissue (Attebery, Adams ; Weiss, 2011). Men have a small amount of nonfunctioning breasts tissue (breast tissue that cannot produce milk) that is concentrated in the area directly behind the nipple on the wall of the chest (Attebery, Adams ; Weiss, 2011). A type of breast cancer that has spread outside of the duct and into the surrounding tissue is called invasive or infiltrating carcinoma (ASC, 2012). Some symptoms that may occur in males developing breast cancer include lumps, changes to the nipple or breast skin, or discharge of fluid from the nipple (National Cancer Institute, 2011). Men who have an altered gene related to breast cancer have an increased risk of developing breast cancer (National Cancer Institute, 2012). The major problem is that breast cancer in men is more often than not diagnosed later than breast cancer in women because men are less likely to be suspicious of an abnormality in that area (Wax, 2012). Also, their small amount of breast tissue is harder to feel, making it more difficult to catch these cancers early, and allowing tumors to spread more quickly to the surrounding tissues (Wax, 2012). Breast cancer in men is detected the same way as breast cancer is detected in women – through self-examination, clinical examination, or mammography (x-ray of the breast) (ASC, 2012). Methods for Diagnosis Breast cancer is sometimes found after symptoms appear, but many women with early breast cancer have no symptoms (American Cancer Society, 2011). This is why getting the recommended screening tests before any symptoms develop is so important (American Cancer Society, 2011). Three types of methods used for diagnosis are mammograms, MRI’s, and biopsies (NCI, 2010). A mammogram is a low-dose x-ray picture of the breast and can be used to check for breast cancer in women who don’t have any signs or symptoms of the disease. (NCI, 2010) The results are recorded on x-ray film or directly into a computer for a doctor called a radiologist to examine (Webmd, 2010). There are different types of mammograms including Screening mammograms and Diagnositc mammograms (Webmd, 2010). Mammograms detect tiny bits of calcium that develop in dead cancer cells (Hoffman, 2010). As more and more cancer cells age and die, theses calcifications grow nd on the mammogram, they appear as a shadowy area (Hoffman, 2010). Current guidelines from the American College Radiology, the American Cancer Society, and the Society for Breast Imaging recommend that women receive annual mammograms starting at age 40, even if they have no symptoms or family history of breast cancer (ACR, 2010). For every 1,000 women who have screening mammogram: 100 are recalled to get more mammogr aphy or ultrasound images, 20 are recommended for needle biopsy and 5 are diagnosed with breast cancer (ACR, 2010). A mammography unit is a rectangular box that houses the tube in which x-rays are produced (Radiological Society of North America, 2011). Once it is carefully aimed at the part of the body being examined, an x-ray machine produces a small burst of radiation that passes through the body, recording an image on photographic film or a special digital image recording plate (Radiological Society of North America, 2011). A brief medical history and a history of specific problems related to the breast, such as pain or a palpable lump (one that is felt), is obtained prior to the mammogram (Stoppler, 2011). All jewelry and clothing in the chest and breast area are removed prior to the mammogram (Stoppler, 2011). The patient’s breasts are then placed on a firm flat panel and a gentle, but firm pressure is applied to the breast with another panel, resulting in compression of the breast between the two panels (Stoppler, 2011). The compression of the breast is necessary to obtain quality mammograms and spreads the breast tissue out so that the x-ray image displays the inner breast tissue with good resolution (Stoppler, 2011). Dense bone absorbs much of the radiation while soft tissue, such as muscle, fat and organs, allow more of the x-rays to pass through them (Radiological Society of North America, 2011). As a result, bones appear white on the x-ray, soft tissue shows up in shades of gray and air appears black (Radiological Society of North America, 2011). The results of the mammogram can be given to the patient either by the radiologist at the completion of the mammogram or by the patient’s doctor who ordered the mammogram (Stoppler, 2011). An abnormal mammogram does not mean you have cancer (Stoppler, 2011). In some cases, it may just be an area of thicker or denser breast tissue, a cyst, or a benign lump such as a fibro adenoma (Stoppler, 2011). Unlike mammography which uses low dose x-rays to produce an image of the breast, MRI (Magnetic Resonance Imaging) uses powerful magnetic fields and radio waves to create images of the breast (Imaginis, 2012). The MRI system has the ability to switch magnetic fields and radio waves to achieve views in any plane and from any orientation while x-ray mammography requires re-orientation of the breast and mammography system for each view desired (Imaginis, 2012). MRI is a huge magnet and the woman gets put in the middle of the magnet; the magnetic field is turned on and then turned off again (Eisenpreis, 1999). The way the magnetized cells return to normal gives an image (Eisenpreis, 1999). The MRI finds lumps better than it tells whether or not they are cancerous (Eisenpreis, 1999). However, MRI can be good at showing how big a cancer is, once it has been found on the mammogram (Eisenpreis, 1999). A breast biopsy removes a sample of breast tissue that is looked at under a microscope to check for breast cancer and is usually done to check a lump found during a breast examination or a suspicious area found on a mammogram, ultrasound, or magnetic resonance imaging (MRI) (Marshall, 2009). During a fine-needle aspiration biopsy, the doctor inserts a thin needle into a lump and removes a sample of cells or fluid (Marshall, 2009). Nowadays, doctors might have decided to do something called stereotactic biopsy, where a patient lies on a table, with her breasts hanging down (Eisenpreis, 1999). A mammogram is taken to show where the lump is and a device holding a needle quickly shoots in and removes a few cells from the lesion (Eisenpreis, 1999). There is also something called a core biopsy that uses a larger needle to take out a piece of tissue, instead of just cells (Eisenpreis, 1999). A doctor numbs your skin with a shot of numbing medicine where the biopsy needle will be inserted and once the area is numb, a small cut is made in the skin from where the needle with a special tip is inserted into breast tissue (Marshall, 2009). Three to twelve samples will be taken to acquire the most accurate results (Marshall, 2009). Classifications and Associated Prognoses The stages of breast cancer are usually expressed as a number on a scale of 0 through IV – with stage 0 describing non-invasive cancers that remain within their original location and stage IV describing invasive cancers that have spread outside the breast to other parts of the body (Marisa, 2011). Cancer stage is based on four characteristics; the size of the cancer, hether the cancer is invasive or non-invasive, whether the cancer is in the lymph nodes, whether the cancer has spread to other parts of the body beyond the breast (Marisa, 2011). Sometimes doctors use the term â€Å"locally advanced†or regionally advanced†to refer to large tumors that involve the breast skin, underlying chest structures, changes to the breast’s shape, and lymph node enlargement that is visible or that the doctor can feel during an exam (Marisa , 2011). The three ways that cancer spreads in the body are: Through tissue where cancer invades surrounding normal tissue, through the lymph system where the cancer invades the lymph system and travels through the lymph vessels to other places in the body, and through the blood, where cancer invades the veins and capillaries and travels through the blood to other places in the body (NCI, 2009). When cancer cells break away from the primary (original) tumor and travel through the lymph nodes or blood to other places in the body, another (secondary) tumor may form (NCI, 2009). This process is called metastasis (NCI, 2009). The stage of the breast cancer can help the patient and the doctor understand the prognosis (the most likely outcome of the disease) and make decisions about treatment, along with all the other results in the pathology report (Marisa, 2011). A staging system is standardized way for the cancer care team to summarize information about how far a cancer has spread (ACS, 2012). The most common system used to describe the stages of breast cancer is the American Joint Committee on Cancer (AJCC) TNM system (ACS, 2012). The TNM staging system classifies cancers based on their T, N, and M stages (ACS, 2012). The letter â€Å"T†followed by a number 0 to 4 describes the tumor’s size and spread to the skin or to the chest wall under the breast (ACS, 2012). The letter â€Å"N†followed by a number from 0 to 3 indicates whether the cancer has spread to lymph nodes near the breast and, if so, how many lymph nodes are affected. The letter â€Å"M†followed by a 0 or 1 indicates whether the cancer has spread to distant organ (ACS, 2012). There are typically five stages (0 to 4) with sub-stages that indicate the prognosis for breast cancer (Lippman, 2005). Stage 0 where the carcinoma is insitu and no lymph nodes are affected had 99 percent 5 year survival rate (ACS, 2012). Stage IA also has a high rate, 92 percent, in which the tumor is equal to 2 centimeters (ACS, 2012). In stage IB, the tumor is 2 centimeters with micro metastases in 1 to 3 axillary lymph nodes but the cancer has not spread to distant sites (ACR, 2012). In stage IIA, the cancer cells have moved to the ipsilateral nodes and the 5 year survival rate lowers to 82 percent (Lippman, 2012). In stage IIB, the cancer cells have spread to movable ipsilateral nodes and the tumor is over 5 centimeters (Lippman, 2012). The 5 year survival rate lowers to 65 percent (ACS, 2012). In stage IIIA, there is no evidence of a primary tumor and no distant spreading (ACS, 2012). The 5 year survival rate lowers to 47 percent (Lippman, 2005). The tumor could be between 2 and 5 centimeters but there is still no distant spreading at this point (ACS, 2012). In stage IIIB the tumor has extended to the chest wall but there is still no distant metastases (Lippman, 2005). The 5 year survival rate lowers again to a 44 percent (Lippman, 2005). In stage IV the cancer can be any size (any T) and may or may not have spread to nearby lymph nodes (any N) (ACS, 2012). It has spread to distant organs or to lymph nodes far from the breast (M1) (ACS, 2012). The most common sites of spread are the bone, liver, brain, or lung (ACS, 2012). The survival rate lowers to 14 percent (Lippman, 2005). Prevention Methods Three ways to prevent breast cancer are by maintaining a healthy weight, avoiding alcohol consumption, and getting an annual mammogram (Reynolds, 2010). Mammogram screening, early diagnosis and better treatments have all contributed to the reduction in breast cancer cases by around 2 percent a year and the improved survival rate in the U. S. (Reynolds, 2010). Experts say now the focus needs to shift on improving personal lifestyle habits to prevent the disease even more (Reynolds, 2010). Early detection of breast cancer with screening mammography means that treatment can be started earlier in the course of the disease, possibly before it has spread (NCI, 2010). A medical team found an 11 percent lower risk of breast cancer in those women consuming the more healthful diet, including more whole grains, fruits and vegetables and less fatty, processed foods (Reynolds, 2010). They also found that those consuming large amounts of alcohol had a 21 percent increased risk (Reynolds, 2010). Drinking alcohol during adolescence has been linked to an increased risk of breast cancer, especially for girls with a family history of the disease (Reynolds, 2010). Exercise also plays a role in the reduction of breast cancer risk (Reynolds, 2010). In one study from the Women’s Health Initiative, as little as 1. 25 to 2. 5 hours per week of brisk walking reduced a woman’s risk by 18 percent (Reynolds, 2010). Walking 10 hours a week reduce the risk more (Reynolds, 2010). Diet and exercise can lead to weight reduction, another positive lifestyle change that can influence breast cancer disease risk (Reynolds, 2010). Many breast cancers are fueled by estrogen, a hormone produced in fat tissue (Reynolds, 2010). Experts suspect that more fat tissue equals more estrogen resulting in more cases of breast cancer that could possibly be avoided (Reynolds, 2010). Genetic ; Hereditary Influence According to researchers, the mutations in the gene, which is called FGFR2, raise the risk of breast cancer by 20 to 60 percent. (Metcalf ; Metcalf, 2008). A genetic mutation that raises the risk of breast cancer is found in up to 60 percent of U. S. omen, making it the first truly common breast cancer susceptibility gene (Metcalf ; Metcalf, 2008). Women with faulty copies of the genes BRCA1 or BRCA2 have 50 percent to 85 percent chance of getting breast cancer in their lifetimes, but they are rare genes and only account for 5 percent to possibly 10 percent of breast cancer cases (Metcalf ; Metcalf, 2008). Only 7% of all breast cancers are hereditary (Hirshaut ; Pressman, 2008). Of these hereditary cancers, 45% is caused by BRCA1 while 35% is caused by BRCA2 (Hirshaut ; Pressman, 2008). (Hirshaut ; Pressman, 2008). Variations of the BRCA1, BRCA2, CDH1, PTEN, STK11, and TP53 genes increase the risk of developing breast cancer (Chen, 2007). The AR, ATM, BARD1, BRIP1, CHEK2, DIRAS3, ERBB2, NBN, PALB2, RAD50, and RAD51 genes are associated with breast cancer (Chen, 2007). Cancers occur when a buildup of genetic mutations in critical genes – those that control cell growth and division or the repair of damaged DNA – allow cells to grow and divide uncontrollably to form a tumor (Honrado, Osorio, Palacios ; Benitez, 2006). These changes, which are called somatic mutations, are not inherited (Honrado, Osorio, Palacios ; Benitez, 2006). Less commonly, gene mutations inherited from a parent increase the risk of developing cancer (Honrado, Osorio, Palacios ; Benitez, 2006). In people with these inherited genetic changes, additional somatic mutations in other genes must occur for cancer to develop (Honrado, Osorio, Palacios ; Benitez, 2006). Additional factors that may influence a person’s risk of developing breast cancer include gender, age, ethnic background, a history of previous breast cancer, certain changes in breast tissue, and hormonal factors (Thompson ; Easton, 2004). A history of breast cancer in closely related family members is also an important risk factor, particularly if the cancer occurred at an early age (Thompson ; Easton, 2004). Women who have inherited certain mutations in these genes have a high risk of developing breast cancer, ovarian cancer, and several other types of cancer during their lifetimes (Thompson ; Easton, 2004). Inherited changes in several other genes, including CDH1, PTEN, STK11, and TP53, have been found to increase the risk of developing breast cancer (Thompson ; Easton, 2004). In hereditary breast cancer, the way that cancer risk is inherited depends on the gene involved (Walsh ; King, 2007). For example, mutations in the BRCA1 and BRCA2 genes are inherited in an autosomal dominant patter, which means one copy of the altered gene in each cell is sufficient to increase a person’s chance of developing cancer (Walsh ; King, 2007). In other cases, the inheritance of breast cancer risk is unclear (Walsh ; King, 2007). It is important to emphasize that people inherit an increased risk of cancer, not the disease itself (Walsh ; King, 2007). Not all people who inherit mutations in these genes will develop cancer (Walsh ; King, 2007). Other Breast Diseases Two other diseases found in the breast other than breast carcinoma are breast fat necrosis and fibrocystic breast disease (Sacks, 2011; Silverman, 1994). Fybrocystic breast disease is a commonly used phrase to describe painful, lumpy breasts (Sacks 2011). Hormones made in the ovaries can make a woman’s breasts feel swollen, lumpy, or painful before during menstruation each month (Sacks 2011). Fibrocysitc changes in the breast with the menstrual cycle affect over half of women (Sacks, 2011). Symptoms are usually worse right before the menstrual period, and then improve after the period starts (Sacks, 2011). Symptoms can include pain in both breasts, breasts that feel swollen and heavy, pain or discomfort under the arms, and thick or lumpy breasts (Sacks, 2011). This disease can be treated with medication like acetaminophen or ibuprofen (Sacks, 2011). Breast Fat necrosis is a benign condition that can occur in your breast (Silverman. 1994). It consists of fatty tissue that has been bruised, injured, or has died (Silverman, 1994). Once fatty tissue has been injured or has died, it can gradually change into scar tissue or may collect as liquid within an oil cyst (Silverman, 1994). Fat necrosis does not lead to the development of breast cancer, but it may sometimes cause breast pain (Silverman, 1994). An area of fat necrosis in your breast may feel like a fairly hard lump, or like a section of thick skin (Silverman, 1994). The person may see some drainage from the nipple that is nearest to the bruised region (Silverman, 1994). The nipple may sometimes even pull inward a little bit or the breast skin may dimple above the lump of fat necrosis (Silverman, 1994). Each case of fat necrosis is unique, so treatments will vary but if the fat necrosis has occurred recently, using warm compresses may help it subside (Silverman, 1994). When fat necrosis causes pain, the person can use ibuprofen and aspirin, but if that doesn’t help, ask your doctor if a prescription medication may be used (Silverman, 1994). About 39,520 women in the U. S. were expected to die in 2011 from breast cancer, though death rates have been decreasing since 1990  especially in women under 50 (â€Å"Learn about cancer,†2011). These decreases are thought to be the result of treatment advances, earlier detection through screening, and increased awareness (â€Å"breastcancer. org,†2012). References Peter, C. (2011, October 20). Medical news today. Retrieved from http://www. medicalnewstoday. com/info/cancer-oncology/ breastcancer. org. (n. d. ). (2012, March 14). Retrieved from http://www. breastcancer. org/symptoms/understand_bc/statistics. jsp Yi-Bin , C. , ; David , Z. (2011, 15 12). A. d. a. m. medical encyclopedia. Retrieved from http://www. ncbi. nlm. nih. gov/pubmedhealth/PMH0001911/ Mayo Clinic Staff. (2011, June 23). Ductal carcinoma in situ (dcis). Retrieved from http://www. mayoclinic. com/health/dcis/DS00983 Avon Foundation Breast Cancer (n. d. ). In http://www. hopkinsmedicine. org/avon_foundation_breast_center/breast_cancers_other_conditions/invasive_lobular_carcinoma. html. Stephan, P. (2008, July 24). Invasive Lobular Carcinoma. Retrieved from about. com website: http://breastcancer. about. com/od/types/p/ilc. html Dugdale, D. (2010, August 14). Pubmed. Retrieved from http://www. ncbi. nlm. nih. gov/pubmedhealth/PMH0002267/ Martin, L. (2012, January 18). Breast cancer facts. WebMD. Retrieved from http://women. webmd. om/guide/breast-cancer-arm-yourself-with-facts National Cancer Insitute. (2012). National cancer institute. Retrieved from http://www. cancer. gov/cancertopics/pdq/treatment/malebreast/Patient/page1 Attebery, L. , Adams, J. H. , ; Weiss, M. (2011, november 22). Male breast cancer. Retrieved from http://www. breastcancer. org/symptoms/types/male_bc/ National Cancer Institute. ( 2011). Male breast cancer. Retrieved from http://www. nlm. nih. gov/medlineplus/malebreastcancer. html Wax, A. (2011). Breast cancer in men: Symptoms, causes, treatments. Retrieved from http://www. webmd. com/breast-cancer/guide/breast-cancer-men American Cancer Society. (2011, September 29). American cancer society. Retrieved from http://www. cancer. org/Cancer/BreastCancer/DetailedGuide/breast-cancer-diagnosis NCI. (2010, September 22). National cancer institute. Retrieved from http://www. cancer. gov/cancertopics/factsheet/detection/mammograms Marshall, S. (2010, November 12). Webmd. Retrieved from http://women. webmd. com/mammogram-16573 Hoffman, M. (2010 February 18). Ductal carcinoma (invasive and in situ. Retrieved from http://www. webmd. com/breast-cancer/ductal-carcinoma-invasive-in-situ ACR. (2012). Mammography facts. Retrieved from http://www. ammographysaveslives. org/facts. aspx Hirshaut, Y. , ; Pressman, P. I. (2008). Breast cancer: The complete guide. (5th ed. ). New York, NY: Bantam Dell. Radiological Society of North America. (2011, June 24). Radiologyinfo. org. Retrieved from http://www. radiologyinfo. org/en/info. cfm? pg=mammo ASCO. (2011, January 26). Breast Cancer- Male Retrieved from http://www. cancer. net/patient/Cancer Types/Breast Cancer – Male/? skid= Stoppler, M. C. (2011). Medicinenet. Retrieved from http://www. medicinenet. com/mammogram/article. html Imaginis. (2012). Breast cancer mri – magnetic resonance imaging. Retrieved from http://www. maginis. com/mri-scan/magnetic-resonance-breast-imaging-mri-mr-3 Eisenpreis, B. (1999). A young woman’s guide to breast cancer prevention. New York: The Rosen Publishing Group. Marshall, S. (2009, April 29). Breast biopsy. Retrieved from http://women. webmd. com/breast-biopsy Metcalf, T. , Metcalf, G. (2008). Perspective on diseases and disorders. (1 ed. ). Michigan: Thomson Gale. Chen, S. ( 2007, April 10). Meta-analysis of BRCA1 and BRCA2 penetrance. Retrieved from http://ghr. nlm. nih. gov/condition/breast-cancer Honrado, E. , Osorio, A. , Palacios, J. , Benitez, J. (2006, September 25). Pathology and gene expression of hereditary breast tumors associated with brca1, brca2 and chek2 gene mutations. Retrieved from http://ghr. nlm. nih. gov/condition/breast-cancer/show/References Thompson, D. , Easton, D. (2004, July 9). The genetic epidemiology of breast cancer genes. Retrieved from http://ghr. nlm. nih. gov/condition/breast-cancer Walsh, T. , King, M. (2007, February 11). Ten genes for inherited breast cancer. Retrieved from http://ghr. nlm. nih. gov/condition/breast-cancer Marisa , W. (2011, August 03). Stages of breast cancer. Retrieved from http://www. breastcancer. org/symptoms/diagnosis/staging. jsp NCI. 2009). Breast cancer treatment (pdq). Retrieved from http://www. cancer. gov/cancertopics/pdq/treatment/breast/Patient/page2 Lippman, M. E. (2005). Cancer monthly. Retrieved from http://www. cancermonthly. com/cancer_basics/breast. asp American Cancer Society. (2012, March 06). Breast cancer. Retrieved from http://www. cancer. org/Cancer/BreastCancer/DetailedG uide/breast-cancer-staging Reynolds, D. (2010, March 26). Emaxhealth. Retrieved from http://www. emaxhealth. com/1506/98/36185/one-third-breast-cancer-cases-avoided-diet-and-exercise. html NCI. (2010, September 22). National cancer institute. Retrieved from http://www. cancer. ov/cancertopics/factsheet/detection/mammograms Sacks, D. N. (2011, November 16). Fibrocystic breast disease. Retrieved from http://www. nlm. nih. gov/medlineplus/ency/article/000912. htm Silverman, P. (1994, July). Breast fat necrosis – symptoms, causes and treatments. Retrieved from http://breastcancer. about. com/od/whenitsnotcancer/tp/Breast-Fat-Necrosis. htm American Cancer Society. U. S. Breast cancer statistics. (2011, September 29). Retrieved from http://www. cancer. org/Cancer/BreastCancer/index Hail, J. (2011, 09). National breast cancer foundation, inc.. Retrieved from http://www. nationalbreastcancer. org/About-Breast-Cancer/ Breast Cancer Breast Cancer
Wednesday, August 28, 2019
Managing Diversity & Equal Opportunity Essay Example | Topics and Well Written Essays - 2000 words
Managing Diversity & Equal Opportunity - Essay Example Provide a list of actions you would need to take as a manager to resolve this issue and also justify your answer. Introduction: Diversity is concerned with recognizing and valuing difference in cultures and ethnicities in the broadest sense. The thing that matters here is to create a working culture and related practices that recognize, respect, value and harness differences for the benefit of the organization as well as the individuals. Trust is an equal opportunities employer, which means that it is the Trust’s policy that there should be no discrimination, harassment, unfair treatment or victimization of any employee, job applicant, customer, provider of services or member of the public, neither directly nor indirectly on the grounds of race, nationality, gender, gender reassignment, marital or family status. Equality means creating a fairer society where everyone can participate and each individual has the opportunity to fulfill his or her potential. It is backed by legisl ations designed to address unfair discrimination based on membership of a particular group. Body: As an HR manager it is my responsibility and so I have the right to stop and prevent harassment and discrimination. Some of the ways in which I can fulfill my task is as follows: Supporting management by developing center policy and procedures for preventing and stopping ill and unfair treatment. Educating staff, particularly through induction and retraining, including specialized training for line managers. Helping the management to establish avenues of assistance at all duty stations for staff members who have experienced harassment or discrimination. Providing direct support and guidance to people involved in such issues Providing guidance to committees investigating harassment and discrimination complaints. Under the current situation, I have come to notice that in the organization some employees in my department are indeed upset, and I have found the reason to be an employee who is racially offensive towards individuals of non-white ethnic origins and discriminated as well as harasses them. As an HR manager, I am responsible for eradicating discrimination and harassment, which is the key to establishing a work place of dignity. To facilitate such an environment, I will ensure that All new appointees, including contractors and consultants, particularly, line managers and supervisors have relevant policies explained to them as part of their induction, early at the time of appointment. Appropriate retraining is given to the workforce from time to time, staffs are reinforced to understand the purpose, ramifications and implications for sustaining a workplace of dignity. Line managers receive specialized training on harassment and discrimination issues as they are the first line of defense and, therefore, must be made thoroughly aware of harassment and discrimination issues. They must act as role models, be alert to the emergence of such mistreatment problems in t heir workgroup and be aware of their responsibilities as they are empowered to act expeditiously and appropriately. It is my duty to solve this problem and as a solution, I would brief the alleged employee to stop his discrimination and to concentrate on the work assigned to him. If he still fails to understand the need to treat his colleagues with respect and
Tuesday, August 27, 2019
UK parliamentary system or USA Essay Example | Topics and Well Written Essays - 250 words
UK parliamentary system or USA - Essay Example The fact that he is not subjected to the legislature in the selection means that he can choose wise men and women with extensive experience (Pushparaj web). In Parliamentary systems, leaders lack the ability to provide effective leadership. Parliamentary leaders often depend on others to perform their duties because they lack the knowledge of the changing world. Presidential systems of government have experienced leaders who perform their duties properly. In addition, parliamentary systems conflict with presidential systems in that secession is common in parliamentary systems. Defection results in nepotism, corruption, and political instability because of the short-lived coalitions. A minister has the discretion and mandates to do that which he deems fit and nobody can exert pressure on him. Presidential system is more democratic than Parliamentary systems. In addition, it is easier to get laws in the USA than in the UK because in USA ministers have a higher level of discretion and mandate to operate than ministers in the UK. However, the British system of government benefits include equal representation of all constituencies both urban and rural, decisions on issues has the say of the majority, and the selection of the prime minister is on the will of majority of members of parliament. Additionally, criticism by the opposition is welcome to the leading government. Pushparaj A. â€Å"What is the difference between Presidential and parliamentary form of Government?†Publish your articles. 2011. Web, 31 May 2012.
Monday, August 26, 2019
BULE Homework 3 Assignment Example | Topics and Well Written Essays - 1000 words
BULE Homework 3 - Assignment Example In matters regarding stock, the S corporation entity would cause the business to enjoy an ability to reach out to latent investors using their stock. Taking this course is beneficial in that expansion becomes a possibility due to the support by money raised from stock issuance. This is an advantage that would be availed in case the cup cake bakery takes the form of Limited Liability Company or sole proprietorship, which lack the capacity to enjoy stock-related benefits. Notably, choosing the S corporation entity would assure the owner of the cup cake bakery of longevity. This is usually the best choice when the owner of the business has in mind long term goals such as creating a perpetual business for subsequent generations. It is a great advantage worth of considering because continuity is assured in case of unexpected incidences such as death unlike in sole proprietorship (Riddle, Butts, and Akiens 5). More importantly, choosing the S corporation entity would be immensely advantage ous because operating within such an entity helps minimize expenses. Summarily, this type of entity excludes owners from paying employment related taxes on a firm’s net revenue. On the other hand, shareholders employed by the cup cake bakery would pay such taxes. What should I name my business? Naming a business can be a stressing ordeal, especially without proper information. For a cup cake bakery, the most suitable name would have to appeal to the customer. In order to ensure that the need for appeal is met, the most suitable name would be ‘Delicious cup cakes’. The use of the word delicious is important in this case, because it appeals to the appetite of individuals who are already like cup cakes. In addition, the word appeals to those who may have never taken cup cakes as well as individuals who take a cup cake occasionally. Additionally, it is a simple name for children. This can work wonders among children because ‘delicious’ is not only appeal ing but also interesting and likely to stick in children’s minds. It is a wonderful name, especially when situating the business in a family neighborhood targeting children and teens. In picking the above name, what made you pick that name and what steps should take when choosing that name? The name ‘delicious cup cakes’ is most preferred because of its simplicity and ability to appeal to appetite. The choice of this name is also based on the basic reason behind customer preference of cup cakes over other baked foodstuffs like bread (Riddle, Butts, and Akiens 11). The bottom line is that people opt for cup cakes because they are deliciously prepared thus the name would trigger unplanned purchasing of the products offered. More importantly, the bakery will offer various types of cup cakes hence using the word delicious helps describe and summarize the varieties on offer. While picking up the name for the bakery, the following steps were necessary. A careful consid eration of other competitive names in the line of business Consideration of the fact that the business captures both shop-related and bakery operations The fact that the business is intended to run for as many years as possible eliminated the use of a personal name A consideration of th
Reflective Portfolio 04243 Essay Example | Topics and Well Written Essays - 3000 words
Reflective Portfolio 04243 - Essay Example The main aspects of CSR activities include the four main aspects which are human rights, labour standards, environment and anti-corruption activities (Leonard and McAdam, 2003). Several companies engage in CSR activities to take care of its social responsibilities. Coca Cola can be one of the examples of the companies who are best known for their CSR. The company has taken up the responsibility to take care of the under privileged and provide child education. It also takes care of the environment by reducing its carbon emission by following the necessary environmental standards. The company has also taken initiatives in water conservation (CSRWire, 2015). The concept of corporate social media is utilizing the social media networks for organizational purposes. Social media can have both positive as well as negative effects on the organizations. There are certain risks involved with the social media. If there is a lack of supervision from the higher authority then there can be a chance of misinterpretation of the organizational activities (Bucaro, 2007). The seminar discussion began with the importance of the corporate social responsibilities and how it is related to the sustainability of the organization. One of the team members started with the example of Beijing TV, exposing the unethical activities of Toyota in China. He mentioned that Toyota deliberately took the advantage of a legal loophole and delivered car with no rear bumper. The car insurance policies only cover standards for the front and side of the car. Although the company did not do anything illegal, however, it definitely showed an irresponsive behaviour towards the consumers. He mentioned that almost all the well established companies are only focused on making money and hardly care for the community. To this ongoing discussion, I added another example of Apple Inc. I mentioned that the company had faced severe accusations of
Sunday, August 25, 2019
The Development Of Diverse Sexual Orientations In Humans Begets Only Research Paper
The Development Of Diverse Sexual Orientations In Humans Begets Only New Versions, Rather Than Presents A Universal Explanation - Research Paper Example While all these people have some thoughts on this issue, hardly somebody of them can clearly operate by well known and scientifically proved arguments that are perceived as a common truth. Biologists, sociologists, psychologists and other professionals do investigate the issue of different sexual orientation among humans, conducting more and more studies and researches in attempts of finding the most reliable answer. Deep studies of the development of diverse sexual orientations in humans begets only new versions, rather than presents a universal explanation There exist many different scientific studies and methodologies aimed at understanding the factors, influencing human sexual orientation. These factors can be differentiated by two or even three categories, including: social factors, biological factors or â€Å"symbioses†of both social and biological factors. Mustanski et al., (2002) in their research review mainly the influence of biological factors on sexual orientation and concludes that biological influences do have impact on human sexual behavior to some extent. While exploring biological influences on sexual orientation, empirical researchers are used to apply two approaches: impact of hormones on development of sexual orientation, and behavioral genetics. ... This research was focused on those drugs which were more likely to affect the hormone level. This link was aslo supported previously by Mustanki et al. (2002) because misbalance of sex hormones levels lead to sexual differentiation of the fetal brain. To be more precise, Mustanski et al. (2002: 97) mentions â€Å"that prenatal hormones hard wire sexual orientation into fetal brains†. For studying the impact of the use of drugs during gestation, researchers have taken a sample of 5102 mothers and collected reports of mothers and their offspring regarding their sexual orientation. According to the results of survey, less than 15% of pregnant women have taken at least one drug or class of drugs, however there was found little evidence on prenatal exposure to drugs among male offspring (Ellis and Hellberg, 2005). While this theory failed to work in relation to male scion, there was evidence that some drugs did have some impact on sexual orientation among female offspring. These we re two types of drugs, which consisted of synthetic thyroid medications and amphetamine-based diet pills (Ellis and Hellberg, 2005). This tendency might be explained by the fact that during the first three months of being pregnant mothers of lesbian offspring did consume high doses of drugs prescribed. From this study there have made a conclusion that prescription drugs such as mentioned above have influence on the immune system of developing female fetuses. Immune system may impact on the processes of feminization of the brain among males, and masculinization of the brain among females. These â€Å"reverse†reactions of the brain might result in different sexual orientations of offspring.
Saturday, August 24, 2019
Testing Required When Applying for a CE Mark for a Medical Device Essay
Testing Required When Applying for a CE Mark for a Medical Device - Essay Example The use of a PE tube is used to hold the cement after sterilization per prescribed, typical methods contained in the standards. The cement is mixed and inserted into the tube to a level flush with the tube. The cement used in a fresh state prior to implanting is also tested for microbiological contamination. As the testing requires a tube to contain the cement for testing a like size rod of equal diameter and length and sanitized per normal procedures will be used as the control. For long term testing of in bone, which is what is required in test the effects of the cement which will be used long term in actual application, selection of the species for test and control is contained in Figure 1 below: Implantation will be done through normally accepted surgical method including shaving the insertion area and thorough antiseptic cleaning of the area and surgery to implant should be performed to minimize any trauma to the area. After insertion sutures are used to close the site and ensure tubes do not loosen or move. After surgery observation is conducted of the test species at appropriate intervals to note and record per 3.3.4 of the standard â€Å"any abnormal findings, including local, systemic and behavioural abnormalities†(p. 5). At the completion of the testing period, in this case 78 weeks the animals will be euthanized humanely in order to determine the biological response of the test area to the prolonged contact with the cement â€Å"by grading and documenting the macroscopic and histopathological test responses as a function of time†(p. 5) and comparing it with the control material (the rods) and the surrounding area. The examination will be facilitated by use of a low magnification lens of each test site material. After all of these results have been documented, the test and control tubes and rods and the surround tissue/bone shall
Friday, August 23, 2019
Who am I in Nursing Leadership - Discussion Essay
Who am I in Nursing Leadership - Discussion - Essay Example Through different seminar that I attended I learned how to become an exceptional charge nurse with good conflict management styles. This paper tries to evaluate the role of leaders in nursing as a profession. The biggest challenge the leaders in the field of nursing face in line with their duties is staffing challenges (Hagler, 2015). This follows the fact that as the economy recover, more of the nurses leave the job markets. The available data supports this current concern and that we need to find nurses who have critical thinking and are moving away from being oriented towards their earning but to be oriented toward their tasks. There should be health care reforms on the revamped functions of the nurses that give the nurses an opportunity to be prepared to deal with the very complex issues relating to health care and even issues dealing with the comprehensive patients in their homes and even within the community level. A lot of the nurse leaders expect that all the nurses to be greatly involved in shaping the health care debate were they establish more interest on the health care legislations. The leaders are encouraging the associations to speak to the law and policy makers about the greater issues affecting nursing. How effective leadership contributes to the proposed improvement remains the central
Thursday, August 22, 2019
Mystic Monk Coffee Essay Example for Free
Mystic Monk Coffee Essay The Wyoming Carmelite monastery was founded by Father Daniel Mary who lived as a Carmelite hermit in Minnesota before moving to Clark, Wyoming, to establish the new monastery. Soon after arriving in Wyoming, Father Daniel Mary had formed the vision of acquiring a new piece of land where he will be building a new monastery with accommodations for 30 monks. This new monastery that Father Daniel Mary has in vision will also be a retreat center for lay visitors, a Gothic Church, a convent for Carmelite nuns, and a hermitage. There were 13 monks dedicated to a life of prayer and worship in the Wyoming Carmelite monastery. Brother Elias, better known as Brother Java, was Mystic Monk Coffee’s master roaster; and ironically is not a coffee drinker. Mystic Monk Coffee had its own website that was responsible for the majority of their sales. Mystic Monk Coffee was also marketed on websites through the ShareASale participation program. A new larger roaster was quoted at $35,000. Father Daniel Mary had a set plan to maximize the potential of monastic opportunities, and realize his vision of buying the Irma Lake Ranch for $8.9 million dollars, and will be the location of the new monastery. Father Daniel Mary is fully aware of the challenge he has in front of him in order to acquire the Irma Lake Ranch. I believe Father Daniel Mary has set definite objectives and performance targets for achieving his goal and I believe that starts with him realizing that the cloistered monastic environment offered unique challenges to operating a business enterprise, but also provides opportunities that were not available to secular businesses. Father Daniel Mary used the word of mouth among loyal customers as a marketing tool in Catholic parishes across the United States. Father Daniel Mary is also fortunate to receive donations, a $250,000 one in particular; but there is also a group of local business owners that had formed the New Mount Carmel Foundation, which helps the monks raise funds. I believe that Mystic Monks Coffee is using the broad differentiation strategy because they are distinguishing that they are different from other coffee companies because of their strong religious background. Through religion the monks are able to market their coffee brand to other Catholic parishes throughout the United States. The monks are able to make $56,500 per month in their first year of operation through sales of coffee and accessories; but they only make a profit of 11 percent from all sales, which is $6,215 a month in revenue. That’s only about $75,000 in profit after their first year of operations. A larger revenue will be needed in order to purchase Irma Lake Ranch. So right now I believe that Father Daniel Mary has made great progress but he is still a long ways away from purchasing a $8.9 million piece of land. Father Daniel Mary resolved to develop an execution plan that would enable Mystic Monk Coffee to minimize the effect of its cloistered monastic constraints, maximize the potential of monastic opportunities, and realize his vision of buying the Irma Lake Ranch. I would consider this a winning strategy because through good faith Mystic Monk Coffee will maximize profits and be embraced by all Catholic parishes in America, and each parish will be able to spread the good word through risk-free marketing. My only recommendation to Father Daniel Mary would to recruit more monks, which will help with the growth of Mystic Monk Coffee. More monks equals more productivity.
Wednesday, August 21, 2019
Alike or Different Essay Example for Free
Alike or Different Essay We can try and change ourselves, by changing our appearance, putting on makeup, wearing different clothes, jewellery, etc. But it’s not just a case of appearance, but it also involves the person underneath that mask everyone tries to hide behind. Nobody has ever tried to look at the person underneath before judging them. It’s just ego that stands in the way. What will the result be when people are stripped of all their accessories, when that mask is removed? What we get is a rollercoaster of emotions. Things that people can never guess are hidden underneath. And that’s yet another similarity, which makes mistaken judgment also put into account. Feelings are also something to look at. For example, people do get happy, angry and sad in different situations, but everyone still gets those emotions at times, regardless of reason. And everyone goes through the same life cycle, how they’re born, turn to children, then the teenage, middle aging comes after, then being old, and finally death. Everyone will face death someday. And everyone is made by God, and made of the same materials, as some believe. Everyone eats and breathes, everyone has the five senses, nobody can live without a vital organ, and no one can have supernatural powers. And these are all similarities. * A lot more people don’t believe in that saying, they believe that people differ in a lot of things, and the things that they have in common with others can be looked at from a different angle, making them into another difference. For example, everyone is a human being, but everyone is a different kind of human being, depending on personality, looks, and abilities. And the fact that everyone has a dream that is to be fulfilled can also be a difference, like everyone has a different dream and a different goal for the future. As for the life, everyone does have a life, but it depends on how they live it, and how everyone uses it that makes a difference. Besides, some people are born to have the personality to be good leaders, and others have the power and will to work hard in what they’re good at, while others don’t treasure their abilities, and instead they use it for their own good, to get the better out of things, while they cause hurt to everyone else around them. That’s an example of being and not being able to be a useful person, to not use life wisely, and another way why people are different. Some believe that people differ in how they look (both on the outside and the inside), how they react to things around them, their personality, beliefs, ethics and religions. What can also count as a difference is how everyone is raised, what they’re taught to believe, where and when they were born and who they lived with. People often adopt habits from those they live with, which can sometimes be good, and sometimes be bad. That can make a lot of differences compared to someone who was born rich, lived rich, and died rich. Another way of looking at things is people’s appearance. Some people really care about how they look, and always try to look their best at times. Some wouldn’t give that subject a second thought. Some do care, but not so much. And that’s related to both personality and physical appearance. Language spoken is also a difference. And the fact that some of us can do something that others can’t, which comes down to ability. Furthermore sometimes people have disabilities that others don’t have. Sometimes there are illnesses and diseases that run in families, and some inherit that disease and some don’t, which is another difference. If we try and list these differences they will not have an end, and just thinking would take long too. So it’s not a case of what is the same and what can be different, it’s just how people think about things in their own point of view. So regardless of what there is that can be used as an argument, and however we think the ones who think the opposite are wrong, and no matter which angle we use look at things, it all goes back to opinion, and opinions are very important. And my opinion stays the same, but what about yours? And what’s more important is to reason why we look at things from that point of view, and if we really are being fair, or if we are just judging others by what we think of them, and how we think of them. And most importantly, are we really being fair, or do we just think we are?
Subscribe to:
Posts (Atom)